Àá½Ã¸¸ ±â´Ù·Á ÁÖ¼¼¿ä. ·ÎµùÁßÀÔ´Ï´Ù.

NaCl ¼ö¿ë¾×¿¡ ´ã±Ù Hydroxyapatite ÄÚÆÃµÈ Å¸ÀÌŸ´½ ½ÃÆíÀÇ Ç¥¸é º¯È­

The Surface Characteristic Changes of Hydroxyapatite Coated Ti Disc When Immersed in NaCl Solution

±¸°­È¸º¹ÀÀ¿ë°úÇÐÁö 2012³â 28±Ç 4È£ p.339 ~ 347
¹é¿¬È­, ±è¸íÁÖ, ±ÇÈ£¹ü, ÀÓ¿µÁØ,
¼Ò¼Ó »ó¼¼Á¤º¸
¹é¿¬È­ ( Baek Yeon-Wha ) - ¼­¿ï´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø Ä¡°úº¸Ã¶Çб³½Ç
±è¸íÁÖ ( Kim Myung-Joo ) - ¼­¿ï´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø Ä¡°úº¸Ã¶Çб³½Ç
±ÇÈ£¹ü ( Kwon Ho-Beom ) - ¼­¿ï´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø Ä¡°úº¸Ã¶Çб³½Ç
ÀÓ¿µÁØ ( Lim Young-Jun ) - ¼­¿ï´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø Ä¡°úº¸Ã¶Çб³½Ç

Abstract

Hydroxyapatite ÄÚÆà ÀÓÇöõÆ®ÀÇ ¼¼Æ÷¹ÝÀÀ¼ºÀ» Áõ°¡½ÃÅ°±â À§ÇÑ ´Ù¾çÇÑ ¿¬±¸µéÀÌ ÁøÇàµÇ¾î ¿Ô´Ù. º» ¿¬±¸¿¡¼­´Â Hydroxyapatite ÄÚÆÃµÈ Å¸ÀÌŸ´½ ½ÃÆíÀ» NaCl ¼ö¿ë¾×¿¡ ´Ù¾çÇÑ ±â°£ µ¿¾È ´ã±×¾î ³õ¾ÒÀ» ¶§ ¹ß»ýÇϴ ǥ¸é°ÅÄ¥±â, Ç¥¸éÁ¢ÃË°¢, Ç¥¸é¿¡³ÊÁö µîÀÇ Ç¥¸é Ư¼ºÀÇ º¯È­¸¦ °üÂûÇÏ¿´´Ù. Hydroxyapatite ÄÚÆà ŸÀÌŸ´½ ½ÃÆíÀ» 0.9% NaCl ¿ë¾×¿¡ ´ã±Ù ÈÄ °¢°¢ 7ÀÏ, 14ÀÏ, 21ÀÏ°£ 37¡É¸¦ À¯ÁöÇÏ¿´´Ù. ´ã±×Áö ¾ÊÀº µ¿ÀÏÇÑ ½ÃÆíÀ» ´ëÁ¶±ºÀ¸·Î ÇÏ¿´´Ù.(n=3) ¸ðµç ½ÃÆíÀ» °ø±â Áß¿¡¼­ ¿ÏÀü °ÇÁ¶ ÈÄ °øÃÊÁ¡·¹ÀÌÀúÁÖ»çÇö¹Ì°æ(CLSM)¸¦ ÀÌ¿ëÇÏ¿© Ç¥¸é°ÅÄ¥±â¸¦ ÃøÁ¤ÇÏ¿´´Ù. Áõ·ù¼ö¸¦ ½ÃÆí Ç¥¸é¿¡ ¶³¾î¶ß¸° ÈÄ Ç¥¸éÁ¢ÃË°¢À» video contact angle analyzer¸¦ ÀÌ¿ëÇÏ¿© ÃøÁ¤ÇÏ¿´°í ¼¼ °¡Áö ¿ë¾×À» ¶³¾î¶ß·Á Á¢ÃË°¢À» ÃøÁ¤ÇÏ¿© Ç¥¸é¿¡³ÊÁö¸¦ »êÃâÇÏ¿´´Ù. Ç¥¸éÀ» °üÂûÇϱâ À§ÇØ Field Emission-Scanning Electron Microscope ÃÔ¿µÀ» ½ÃÇàÇÏ¿´´Ù. º» ¿¬±¸ °á°ú Hydroxyapatite ½ÃÆíÀ» Nacl ¼ö¿ë¾×¿¡ ´ã±×´Â °£´ÜÇÑ ¹æ¹ýÀ» ÅëÇØ Ç¥¸é°ÅÄ¥±â ¹× Ä£¼ö¼ºÀÌ Áõ°¡ÇÏ´Â °ÍÀ» °üÂûÇÒ ¼ö ÀÖÀ¸¸ç, ÀÌ·¯ÇÑ Ç¥¸éƯ¼ºÀÇ °³¼±À» ÅëÇÏ¿© ¼¼Æ÷¹ÝÀÀ¼ºÀÌ Áõ°¡ÇÏ
´Â °ÍÀ» ±â´ëÇÒ ¼ö ÀÖ´Ù.

In previous studies, methods for enhancing cellular response on the Hydroxyapatite coated implant surface were
described. In this study, the changes of surface characteristics such as surface roughness, contact angle, surface energy
and surface morphology were observed when Hydroxyapatite coated Ti discs were immersed in NaCl solution for various
time. Hydroxyapatite coated Ti discs were immersed in 0.9% NaCl solution for 7, 14 and 21 days at 37¡É. The control
group comprises dry identical discs not immersed in a solution. (n=3) All discs were dried in air completely and the surface roughness was measured using confocal laser scanning microscopy(CLSM). Static contact angle was recorded by video contact angle analyzer after dropping distilled water on the surface. The surface energy was calculated from contact angles of the three liquids. Surface was observed using a field emission-scanning electron microscope(FE-SEM).
As a result, the surface roughness of immersed Hydroxyapatite coated Ti discs increased significantly and the contact
angle decreased comparing with control group discs. The surface energy of immersed discs increased except for discs
immersed for 14 days.

Å°¿öµå

Hydroxyapatite ÄÚÆà ÀÓÇöõÆ®;Ç¥¸é°ÅÄ¥±â;Ç¥¸éÁ¢ÃË°¢;Ç¥¸é¿¡³ÊÁö;Ä£¼ö¼º
contact angle;hydrophilicity;Hydroxyapatite coated implant;surface energy;surface roughness

¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸

 

µîÀçÀú³Î Á¤º¸

KCI